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Bradley T.
Christian Ph.D. , University of Wisconsin-Madison Director of PET Physics, Waisman Brain Imaging Lab Assistant Professor of Medical Physics and Psychiatry
Contact Information |
Selected Publications
Last updated 2/22/2006 by rowley@waisman.wisc.edu
Research Interests
Our research focuses on developing and translating novel PET methods for the
study of neuropsychiatric illness. This involves using PET methodologies to
investigate neurochemical changes in the brain and studying novel radioligands
to characterize neurotransmitter-protein interactions and how they are
influenced by the effects of psychotropic drugs. These imaging methods are being
applied to investigate the etiologies and mechanisms in diseases such as
affective disorders, schizophrenia, Alzheimer's disease and Tourette syndrome.
Christian BT, Narayanan TK, Shi B, Morris ED, Mantil J, Mukherjee J.
Measuring the In Vivo Parameters of [18F]-Fallypride in Monkeys Using a PET
Multiple-Injection Protocol. Journal of Cerebral Blood Flow and
Metabolism. 24(3): 309-322, 2004.
Lehrer DS, Christian BT, Mantil J, Murray A, Buchsbaum BR, Oakes TR, Byne W,
Buchsbaum MS.
Thalamic and prefrontal FDG uptake in never-medicated patients with
schizophrenia. American Journal of Psychiatry. 162:132-138, 2005.
Mukherjee J, Christian BT, Narayanan T, Shi B, Collins BT.
Measurement of d-amphetamine-induced effects on the binding of dopamine D2/D3
receptor radioligand, [F-18]fallypride in the extrastriatal brain regions in
nonhuman primates using PET. Brain Research 1032(1-2):77-84, 2005.
Muzic RF, Christian BT. Evaluation of Objective Functions for Estimation of
Kinetic Parameters. Medical Physics (In Press 2006).
Christian BT, Lehrer DL, Shi B, Narayanan TK, Strohmeyer PS, Buchsbaum MS,
Mantil JC. Measuring Dopamine Neuromodulation in the Thalamus: Using
[F-18]fallypride PET to study dopamine release during a spatial attention task
NeuroImage (In Press 2006).
Click to search National Library of Medicine and PubMed for other publications by Dr. Christian