Department of Medical Physics

University of Wisconsin - School of Medicine and Public Health

Madison, Wisconsin

Medical Physics Seminar - Monday, September 28, 2009


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Radiation Dose Reduction in Dynamic, Contrast-Enhanced Cerebral Computed Tomography

Mark Supanich

Research Assistant

Department of Medical Physics

UW-School of Medicine and Public Health

Madison, Wisconsin

Dynamic, contrast-enhanced cerebral imaging protocols including Computed Tomography Angiography (CTA) and CT Perfusion (CTP) are vital diagnostic tools to assess neurovascular disease.  However, radiation dose delivered to patients in time-resolved CT protocols is high and potential risk associated with the ionizing radiation dose exists. In order to reduce the radiation dose delivered during dynamic, contrast-enhanced CT applications, the CT formulation of HighlY constrained back PRojection (HYPR) imaging is applied to dynamic cerebral CT imaging.  Experimental results demonstrate that a factor of 6-8 times radiation dose reduction for time-resolved CTA, a factor of 4 times radiation dose reduction for CTP and axial resolution improvements of a factor of 4 are possible when the HYPR algorithm is applied to time-resolved cerebral CT imaging protocols.

Location: 1345 Health Sciences Learning Center (HSLC)

Time:  4:00pm-5:00pm

Refreshments will be provided prior to the talk


 last modified  9/03/2009/jk

QUICK LINKS: [Medical Physics Home Page] [Seminar Home Page]