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Focus Area 3: Imaging for treatment assessment

Imaging has started to emerge as a potential biomarker of clinical treatment response. Pre-treatment characterization of tumor phenotypes allows for stratification of patients into different treatment regimes. Early assessment and prediction of treatment response allows for individualized re-optimization of therapy. We are performing a series of Phase I clinical trials utilizing advanced molecular imaging to determine early treatment response and pharmacodynamics of several novel drugs, particularly targeting angiogenesis.

Projects

  1. Imaging biomarkers of treatment response (Peter Scully)
  2. Heterogeneity of Response in Hematological Malignancy (Natalie Weisse)
  3. Deformable registration in treatment assessment (Stephen Yip)


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