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Paul Campagnola

Paul Campagnola, Ph.D.


Department Affiliations

Medical Physics

Biomedical Engineering

LOCI (Laboratory for Optical and Computational Instrumentation)


B.A., Chemistry, Colgate University

Ph.D., Physical Chemistry, Yale University

Research Interests


Tissue imaging

Breast and Ovarian Cancer

Connective Tissue Disorders


Cancer Cell Biology

Tissue Engineering


  • Biophysical Society
  • Optical Society of America


  • S. Plotnikov, V. Juneja, A. Isaacson, W.A. Mohler, and P. J. Campagnola, Optical Clearing for Improved Contrast in Second Harmonic Generation Imaging of Skeletal Muscle, Biophys. J.,90, 328-339 (2006)
  • S. Plotnikov, A.C. Millard, P.J. Campagnola, and W.A. Mohler, Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres. Biophys J., 90, 693-703, (2006).
  • L.P. Cunningham, M.P. Veilleux, and P.J. Campagnola, Freeform multiphoton excited microfabrication for biological applications using a rapid prototyping CAD-based approach, Optics Express, 14, 8613-8621 (2006).
  • R. LaComb, O. Nadiarnykh, S. Townsend, and P.J. Campagnola, Phase Matching considerations in Second Harmonic Generation from tissues: Effects on emission directionality, conversion efficiency and observed morphology, Optics Comm, 281, 1823-1832 (2008).
  • R. LaComb, O. Nadiarnykh, and P.J. Campagnola, Second Harmonic Generation imaging of osteogenesis imperfecta: experiment and simulation?, Biophys. J., 94, 4504-4514 (2008).
  • R. LaComb, O. Nadiarnykh, S. Carey and P.J. Campagnola, Quantitative SHG imaging and modeling of the optical clearing mechanism in striated muscle and tendon J. Biomed Opt. 13, 021108 (2008).
  • X. Chen, M.A. Brewer,C. Zou and P.J. Campagnola, Migration and adhesion of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry, Integrative Biology, 1, 469?476 (2009).
  • O. Nadiarnykh and P. J. Campagnola, Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing, Optics Express, 17, 5794-5806 (2009)

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