Medical Physics Seminar – Monday, October 11, 2010
*SPECIAL 1309 HSLC, 12noon* PET Imaging Agents for Alzheimers Disease
Jogesh Mukherjee, Ph.D. (guest of Dr. Brad Christian)
Professor and Director, Preclinical Imaging, Department of Psychiatry & Human Behavior, Physiology & Biophysics And Radiological Sciences, University of California-Irvine
Development of beta-amyloid plaques and neurofibrillary tangles is the
hallmark of Alzheimers disease (AD) and progressively affects the overall
functioning of the brain. Noninvasive imaging methods aiding early diagnosis
will significantly improve benefits provided by treatments and possibly lead
to prevention of AD. This talk will present the development of PET
radiotracer methods for beta-amyloid plaques and tangles, nicotinic alpha 4
beta 2 receptors, serotonin 5HT1A receptors, dopamine D2/D3 receptors and
norepinephrine transporters for the study of AD.