Medical Physics Seminar – Monday, September 28, 2020
Optical Metasurfaces for Label-free Biosensing and Bioimaging Applications
Filiz Yesilkoy
Assistant Professor, University of Wisconsin–Madison,Department of Biomedical Engineering
Mobile, affordable and reliable biochemical sensors that can drastically reduce the detection time by enabling multiple biomarker detection from small sample volumes are essential for effective next-generation healthcare. Unfortunately, current biosensing methods require laboratory infrastructure, trained personnel, complex and costly bioassay protocols. Nanophotonic biosensors can detect biomolecules in a label-free and non-destructive manner based on the enhanced light-matter interactions at nanoengineered surfaces. In this talk, I will give an overview on the nanophotonic biosensors particularly emphasizing miniaturized portable bioanalytical platforms that enable on-site applications, highlighting the results from a clinical study designed to detect Sepsis biomarkers from patient samples. Moreover, I will discuss the use of high-Q dielectric metasurfaces for hyperspectral biomolecule imaging.