The UW School of Medicine and Public Health, Paul Carbone Cancer Research Imaging Center, and the Department of Medical Physics support a Visualsonics Vevo 2100 and Vevo LAZR ultrasound and photoacoustic small animal imaging housed in the Small Animal Imaging Facility (SAIF), B1334, Wisconsin Institutes for Medical Research (WIMR) Tower 1, 1111 Highland Avenue, Madison, WI 53705-2275.
The Vevo 2100 is a high frequency array-based ultrasound system with center frequencies in the 20-70 MHz center frequency range. More details on system capability are provided here.
Photoacoustic imaging uses non-ionizing laser pulses which are delivered into biological tissues and/or contrast agents creating a small amount of heat noninvasively. This subtle heat creates a momentary thermoelastic expansion of the tissue/contrast agent at the ultrasonic emission wavelength, which is detected by traditional ultrasound transducers. More information on this process and system is available here.