Robert Jeraj


Professor (tenure), Medical Physics


7033 WIMR



Robert Jeraj, Ph.D.

Professor (tenure), Medical Physics

Department Affiliations

Medical Physics

Human Oncology


B.Sc., Physics, University of Ljubljana, Slovenia

Ph.D., Physics, University of Ljubljana, Slovenia

Research Interests

Image guided therapy for cancer

  • Molecular imaging
  • Radiation therapy
  • Optimization
  • Monte Carlo modeling
  • Dosimetry


  • American Association of Physicists in Medicine (AAPM)
  • European Society of Therapeutic Radiology and Oncology (ESTRO)
  • Australiasian College of Physical Scientists and Engineers in Medicine (ACPSEM)
  • American Nuclear Society (ANS)
  • European Nuclear Society (ENS)
  • Institute of Physics (IoP; Fellow)


  • System and method for evaluation of disease burden, Wisconsin Alumni Research Foundation, U.S. Patent No. 9603567B2.
  • System and method for gradient assisted non-connected automatic Region (GANAR) analysis, Wisconsin Alumni Research Foundation, U.S. Patent No. 20150055849A1.
  • Treatment Planning System For Radiopharmaceuticals, Wisconsin Alumni Research Foundation, U.S. Patent No. 20110060602A1.
  • Method and apparatus for low dose computed tomography, Wisconsin Alumni Research Foundation, U.S. Patent No. EP1973469A2.
  • Small Field Intensity Modulated Radiation Therapy Machine, Wisconsin Alumni Research Foundation, U.S. Patent No. 20070242801A1.
  • Correction of patient rotation errors in radiotherapy using couch translation, Wisconsin Alumni Research Foundation, U.S. Patent No. 7302038B2.

Publications (view PubMed for an up-to-date list)

  • Adhikarla, V and Jeraj, R, An imaging-based stochastic model for simulation of tumour vasculature, Phys Med Biol 57(19), 6103-6124 (2012).
  • Bowen, SR, Chappell, RJ, Bentzen, SM, Deveau, MA, Forrest, LJ, and Jeraj, R, Spatially resolved regression analysis of pre-treatment FDG, FLT and Cu-ATSM PET from post-treatment FDG PET: An exploratory study, Radiother Oncol (2012).
  • De Ruysscher, D, Nestle, U, Jeraj, R, and Macmanus, M, PET scans in radiotherapy planning of lung cancer, Lung Cancer 75(2), 141-5 (2012).
  • Gregoire, V, Jeraj, R, Lee, JA, and O’Sullivan, B, Radiotherapy for head and neck tumours in 2012 and beyond: conformal, tailored, and adaptive?, Lancet Oncol 13(7), e292-300 (2012).
  • Grudzinski, JJ, Floberg, JM, Mudd, SR, Jeffery, JJ, Peterson, ET, Nomura, A, Burnette, RR, Tome, WA, Weichert, JP, and Jeraj, R, Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT, Phys Med Biol 57(6), 1641-1657 (2012).
  • Kubicek, LN, Seo, S, Chappell, RJ, Jeraj, R, and Forrest, LJ, Helical tomotherapy setup variations in canine nasal tumor patients immobilized with a bite block, Vet Radiol Ultrasound 53(4), 474-81 (2012).
  • Titz, B, Kozak, KR, and Jeraj, R, Computational modelling of anti-angiogenic therapies based on multiparametric molecular imaging data, Phys Med Biol 57(19), 6079-6101 (2012).
  • Vanderhoek, M, Perlman, SB, and Jeraj, R, Impact of the definition of peak standardized uptake value on quantification of treatment response, J Nucl Med 53(1), 4-11 (2012).
  • Balter, JM, Haffty, BG, Dunnick, NR, Siegel, EL, and Jeraj, R, (Imaging Opportunties Workshop Participants), Imaging opportunities in radiation oncology, Int J Radiat Oncol Biol Phys 79(2), 342-7 (2011).
  • Bortfeld, T and Jeraj, R, The physical basis and future of radiation therapy, Br J Radiol 84(1002), 485-98 (2011).
  • Bowen, SR, van der Kogel, AJ, Nordsmark, M, Bentzen, SM, and Jeraj, R, Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modeling, Nucl Med Biol 38(6), 771-80 (2011).
  • Liu, G, Jeraj, R, Vanderhoek, M, Perlman, S, Kolesar, J, Harrison, M, Simoncic, U, Eickhoff, J, Carmichael, L, Chao, B, Marnocha, R, Ivy, P, and Wilding, G, Pharmacodynamic Study Using FLT PET/CT in Patients with Renal Cell Cancer and Other Solid Malignancies Treated with Sunitinib Malate, Clin Cancer Res 17(24), 7634-44 (2011).
  • Simoncic, U and Jeraj, R, Cumulative input function method for linear compartmental models and spectral analysis in PET, J Cereb Blood Flow Metab 31(2), 750-6 (2011).
  • Vanderhoek, M, Juckett, MB, Perlman, SB, Nickles, RJ, and Jeraj, R, Early assessment of treatment response in patients with AML using [(18)F]FLT PET imaging, Leuk Res 35(3), 310-6 (2011).
  • Barbee, DL, Flynn, RT, Holden, JE, Nickles, RJ, and Jeraj, R, A method for partial volume correction of PET-imaged tumor heterogeneity using expectation maximization with a spatially varying point spread function, Phys Med Biol 55(1), 221-36 (2010).
  • Deveau, MA, Bowen, SR, Westerly, DC, and Jeraj, R, Feasibility and sensitivity study of helical tomotherapy for dose painting plans, Acta Oncol 49(7), 991-6 (2010).
  • Galavis, PE, Hollensen, C, Jallow, N, Paliwal, B, and Jeraj, R, Variability of textural features in FDG PET images due to different acquisition modes and reconstruction parameters, Acta Oncol 49(7), 1012-6 (2010).
  • Grudzinski, JJ, Burnette, RR, Weichert, JP, and Jeraj, R, Dosimetric effectiveness of targeted radionuclide therapy based on a pharmacokinetic landscape, Cancer Biother Radiopharm 25(4), 417-26 (2010).
  • Grudzinski, JJ, Tome, W, Weichert, JP, and Jeraj, R, The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model, Phys Med Biol 55(19), 5723-34 (2010).
  • Jeraj, R, Cao, Y, Ten Haken, RK, Hahn, C, and Marks, L, Imaging for assessment of radiation-induced normal tissue effects, Int J Radiat Oncol Biol Phys 76(3 Suppl), S140-4 (2010).
  • Korreman, SS, Ulrich, S, Bowen, S, Deveau, M, Bentzen, SM, and Jeraj, R, Feasibility of dose painting using volumetric modulated arc optimization and delivery, Acta Oncol 49(7), 964-71 (2010).
  • McCall, KC, Barbee, DL, Kissick, MW, and Jeraj, R, PET imaging for the quantification of biologically heterogeneous tumours: measuring the effect of relative position on image-based quantification of dose-painting targets, Phys Med Biol 55(10), 2789-806 (2010).